Belly fat isn't passive. It releases inflammatory chemicals that make your body resistant to insulin. It's directly linked to:
- Type 2 diabetes
- High blood pressure
- Fatty liver disease
- Heart attacks and stroke
Loading...
Find your protocol
Choose the peptide and delivery format that fits your protocol. Each prescribed by a licensed clinician, dispensed by a 503A pharmacy.
Sermorelin · Injection
Sermorelin Injection
The gentler, foundational GHRH analog. Best for sleep, recovery, and gradual body composition.
Sermorelin · Nasal
Sermorelin Nasal Spray
Same molecule as the injection, needle-free. Best for daily compliance.
Tesamorelin · Strongest
Tesamorelin Injection
The stronger, longer-acting molecule. Strongest evidence for visceral fat and advanced longevity protocols.
Multi-month savings (10% / 15%) unlock from your patient portal after your first order.
A note on our packaging
Notice our bottles are not labeled.
That's intentional. We do not white-label our medications. Your dispensing pharmacy applies the official prescription label, with their name, your name, and full lot details, at the moment your order is filled. You will always know exactly which licensed 503A pharmacy compounded your medication.
Growth Hormone Peptide Therapy
Sermorelin Injection
The original GHRH peptide
Pre-mixed vial · Ready to use · Subcutaneous · Cold-chain shippedThe original, well-tolerated entry point to GHRH peptide therapy. Best for sleep, recovery, and gradual body composition.
The peptide most people are actually asking for.
- Targets belly fat, the deep fat around your organs
- Helps you keep and build lean muscle
- Tells your brain to release its own growth hormone, the way it did when you were younger
Other things it helps with.
- Deeper sleep and faster recovery
- Better skin and hair
- Stronger, leaner body
Up to 40% of weight lost on GLP-1s is muscle.1 Growth hormone peptides help keep the muscle, and target belly fat.
1Wilding JPH et al., STEP-1 substudy, Diabetes, Obesity and Metabolism (2021).
Your body does the work.
Sermorelin signals your brain to release your own growth hormone.
Your safety switch stays on.
- Your brain controls the dose, so it's hard to overshoot
- Unlike synthetic HGH, which can overshoot and cause permanent changes to bone and facial structure
IGF-1 delivers the benefits.
Your liver turns growth hormone into IGF-1 (a repair signal), which drives:
- Faster recovery
- Lean muscle
- Better skin
- Deeper sleep
- More energy
Why now.
Natural growth hormone drops about 14% every decade after age 30.
- Pre-mixed Sermorelin vial, freshly compounded by a 503A pharmacy
- Sterile insulin needles, one per dose
- Alcohol prep wipes
- Message your care team directly through the dashboard
- Cold-chain shipped, refrigerate on arrival (36-46°F). Do not freeze.
- We do not white-label our medications.
- Your dispensing 503A pharmacy applies the official prescription label at fill
- Label shows pharmacy name, your name, lot number, and dispensing details
- You will always know exactly which licensed pharmacy compounded your medication
- Subcutaneous, typically before bed (mirrors your natural overnight GH pulse)
- Vial arrives pre-mixed and ready to use, no reconstitution required
- Drawn directly into a sterile insulin syringe
- Dose is personalized by your provider based on goals, age, and IGF-1 labs
The most direct, most reliable way to deliver Sermorelin.
- Delivered under the skin, bypassing the gut and nose where most of the peptide would get broken down
- Strongest brain signal to release your own growth hormone
- Most consistent dose, every time, with no variation from nasal absorption
- Timed before bed matches your body's natural overnight growth hormone pulse
- Patients typically notice deeper sleep and faster recovery in the first few weeks
- Lean muscle and body composition changes follow over 2 to 3 months
- The pre-mixed vial means no powder mixing, just draw and inject
- Tirzepatide and Semaglutide: up to 40% of weight lost on GLP-1s is lean muscle. Sermorelin helps preserve it.
- Glutathione & NAD+: broader longevity protocol
Currently shipping to: TX, CA, FL, NY. Additional states added regularly.
$180.00
One month supply
Sermorelin Injection - First Month
$180.00
Freshly compounded, pre-mixed vial, ready to use. Includes cold-chain shipping, sterile needles, alcohol wipes, consultation, and provider support. Multi-month bundle discounts (3-month: 10% off · 6-month: 15% off) unlock from your patient portal after your first order.
- US Licensed Doctors and 503A Pharmacies
- Free Cold-Chain Shipping
- FSA & HSA Eligible
A note on our packaging
Notice our bottles are not labeled.
That's intentional. We do not white-label our medications. Your dispensing pharmacy applies the official prescription label, with their name, your name, and full lot details, at the moment your order is filled. You will always know exactly which licensed 503A pharmacy compounded your medication.
Growth Hormone Peptide Therapy
Sermorelin Nasal Spray
The original peptide, no needles required
Pre-filled metered bottle · Ready to use · Cold-chain shippedThe same Sermorelin molecule as the injection, in a needle-free nasal spray. A good fit for daily compliance and patients new to peptide therapy.
The same growth hormone benefits, no needles.
- Same brain signal to release growth hormone, just delivered through the nose
- Helps you keep and build lean muscle
- Great if you don't want injections, or want to skip a day
Other things it helps with.
- Deeper sleep and faster recovery
- Better skin and hair
- Stronger, leaner body
Up to 40% of weight lost on GLP-1s is muscle.1 Growth hormone peptides help keep the muscle, and target belly fat.
1Wilding JPH et al., STEP-1 substudy, Diabetes, Obesity and Metabolism (2021).
- Nasal mucosa is one of the few non-injection routes that delivers peptides without first-pass digestion
- Bioavailability is lower than injection, clinician calibrates dose accordingly
- Same downstream pathway as the injection: GHRH → brain → GH → IGF-1
- Needle-free. For patients new to peptides or anyone who simply prefers not to inject
- Metered dose every spray. The bottle delivers a precise dose with each actuation, no syringe drawing required
- Pocketable and discreet. Unlike a vial-and-syringe protocol, the bottle travels with you and reads as a regular nasal spray
- Best for nightly compliance. Many patients report the nasal protocol is easier to stick with long-term
- Dose-flexible. Your clinician can adjust your daily spray count without changing the bottle
- Pre-filled, metered Sermorelin nasal bottle, freshly compounded by a 503A pharmacy
- Message your care team directly through the dashboard
- Cold-chain shipped, refrigerate on arrival (36-46°F). Do not freeze.
- Discard after the pharmacy's printed use-by date
- We do not white-label our medications.
- Your dispensing 503A pharmacy applies the official prescription label at fill
- Label shows pharmacy name, your name, lot number, and dispensing details
- You will always know exactly which licensed pharmacy compounded your medication
- Intranasal, typically in the evening (mirrors your natural overnight GH pulse)
- Bottle arrives pre-filled, no mixing required
- Dose is personalized by your provider based on goals, age, and prior peptide experience
- Tirzepatide and Semaglutide: up to 40% of weight lost on GLP-1s is lean muscle. Sermorelin helps preserve it.
- Glutathione & NAD+: broader longevity protocol
$180.00
One month supply
Sermorelin Nasal Spray - First Month
$180.00
Pre-filled metered nasal bottle. Includes shipping, consultation, and provider support. Multi-month bundle discounts (3-month: 10% off · 6-month: 15% off) unlock from your patient portal after your first order.
- US Licensed Doctors and 503A Pharmacies
- Free Cold-Chain Shipping
- FSA & HSA Eligible
A note on our packaging
Notice our bottles are not labeled.
That's intentional. We do not white-label our medications. Your dispensing pharmacy applies the official prescription label, with their name, your name, and full lot details, at the moment your order is filled. You will always know exactly which licensed 503A pharmacy compounded your medication.
Growth Hormone Peptide Therapy
Tesamorelin Injection
The stronger, longer-acting peptide
Pre-mixed vial · Ready to use · Subcutaneous · Cold-chain shippedThe strongest growth hormone peptide available. Longer-lasting in your body. Stronger, more sustained signal to release growth hormone.
The strongest option for belly fat.
- FDA-approved to reduce belly fat, the only growth hormone peptide that is2
- Tells your brain to release growth hormone more strongly than Sermorelin
- Helps you keep lean muscle while you lose fat
Other things it helps with.
- Sharper focus and mental clarity
- Healthier cholesterol and metabolism
- Better skin and recovery
Up to 40% of weight lost on GLP-1s is muscle.1 Tesamorelin is the only growth hormone peptide FDA-approved to reduce belly fat.2
1Wilding JPH et al., STEP-1 substudy, Diabetes, Obesity and Metabolism (2021). 2Falutz J et al., New England Journal of Medicine (2007). Egrifta® (tesamorelin) approved 2010 for HIV-associated lipodystrophy. Off-label use is determined by the prescribing clinician.
Sturdier molecule that lasts 2-3× longer in your bloodstream.
- More GH released by your brain
- More IGF-1 produced by your liver
- Stronger downstream benefits
FDA approved to reduce visceral fat.*
The deep belly fat wrapped around your organs that is hardest to lose (and the most dangerous).
Same natural pathway, stronger input.
- Your brain still controls the dial
- Your safety switch still stays on
- Tesamorelin just turns up the input signal
Sermorelin is the gentler entry point. Tesamorelin is the stronger response.
For the science-curious: 44-amino-acid GHRH analog stabilized with a trans-3-hexenoic acid modification.
*Egrifta (tesamorelin) is approved for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy.
- Pre-mixed Tesamorelin vial, freshly compounded by a 503A pharmacy
- Sterile insulin needles, one per dose
- Alcohol prep wipes
- Message your care team directly through the dashboard
- Cold-chain shipped, refrigerate on arrival (36-46°F). Do not freeze.
- We do not white-label our medications.
- Your dispensing 503A pharmacy applies the official prescription label at fill
- Label shows pharmacy name, your name, lot number, and dispensing details
- You will always know exactly which licensed pharmacy compounded your medication
- Subcutaneous, typically before bed (mirrors your natural overnight GH pulse)
- Vial arrives pre-mixed and ready to use, no reconstitution required
- Drawn directly into a sterile insulin syringe
- Stronger response than Sermorelin, clinician calibrates dose carefully
- Some patients begin on Sermorelin and graduate to Tesamorelin; others start directly
- Tirzepatide and Semaglutide: up to 40% of weight lost on GLP-1s is lean muscle. Tesamorelin's stronger GH response helps preserve and rebuild it.
- Glutathione & NAD+: broader longevity protocol
Currently shipping to: TX, CA, FL, NY. Additional states added regularly.
$299.00
One month supply
Tesamorelin Injection - First Month
$299.00
Freshly compounded, pre-mixed vial, ready to use. Includes cold-chain shipping, sterile needles, alcohol wipes, consultation, and provider support. Multi-month bundle discounts (3-month: 10% off · 6-month: 15% off) unlock from your patient portal after your first order.
- US Licensed Doctors and 503A Pharmacies
- Free Cold-Chain Shipping
- FSA & HSA Eligible
How it Works
1. Purchase and Medical History
Complete a brief health history at checkout. No charge unless approved.
2. Clinical Review
A licensed physician reviews your intake and, if appropriate, prescribes your protocol. Medications ship from a licensed 503A pharmacy.
3. At-Home Therapy
Simple self-administration, free cold-chain shipping, and ongoing support from your care team.
Lose fat,
not just weight.
The compliment changes.
People on GLP-1s hear "you lost weight."
People on growth hormone peptides hear "you look good."
Losing weight and losing fat are not the same thing.
GLP-1s shrink the scale. But up to 40% of that loss is lean mass, including muscle and the facial fat that keeps you looking like yourself.1 Smaller, but flatter. Smaller, but older.
Sermorelin and Tesamorelin do the opposite. They target the deep belly fat that drives health risk, while signaling your body to preserve and build lean muscle.
Less belly. More muscle. Better skin and hair, all from the same pathway.
Lose fat, not just weight.
Three reasons this matters.
Lose muscle in your 40s and 50s and it's hard to rebuild. Muscle and bone drive:
- Strength and how you look
- How fast you burn calories
- Bone density and joint support
- How long you live well
- HGH adds growth hormone from outside. Your brain makes less of its own over time.
- Sermorelin and Tesamorelin prompt your brain to release the growth hormone it already makes.
- Cycled properly under provider supervision, you support a healthy growth hormone signal without shutting down your body's own controls.
- When you stop, your body returns to baseline. Nothing is shut down.
- Tesamorelin is the only growth hormone peptide FDA-approved to reduce belly fat.3
1Wilding JPH et al., STEP-1 trial body composition substudy, Diabetes, Obesity and Metabolism (2021); Heymsfield SB et al., JAMA (2021). Lean mass loss varies by intervention, dose, age, baseline body composition, and concurrent activity.
2Mahabadi AA et al., European Heart Journal (2013); Britton KA et al., Journal of the American College of Cardiology (2013).
3Falutz J et al., New England Journal of Medicine (2007). Egrifta® (tesamorelin) approved by the FDA in 2010 for reduction of excess abdominal fat in HIV-associated lipodystrophy. Off-label use is determined by the prescribing clinician.
Who is this for?
For adults who feel the gap between how their body responds now and how it did a decade ago.
May improve these areas
- Sleep deeper
- Lose visceral fat
- Recover faster
- Build lean muscle
- Skin quality, firmness, and thickness
- Focus, memory, clarity
- Lower triglycerides and liver fat
- Motivation, resilience, mental stamina
- Cellular repair and telomerase length
- Strengthen immunity
- Increase bone density
Ready to feel the difference?
Order Now
What you can expect
Results build gradually. Individual response varies. Here's the arc many patients describe:
Month 1
Deeper sleep. Better recovery between training sessions. Most patients notice within 2 to 4 weeks.
Month 2
Your body starts to change shape. Leaner, more toned. Energy more consistent. Tesamorelin patients often see belly fat reduction here.
Month 3 and beyond
Continued body shape improvement. Stronger recovery. Better skin (firmer, more hydrated, more elastic). More energy. Many patients describe it as "feeling like myself again."
Important: Sermorelin and Tesamorelin are compounded medications dispensed by licensed 503A pharmacies under a valid prescription. They are not FDA-approved for the uses described on this page, and are not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. Information on this page is for general education and does not replace clinical advice from your prescribing provider.
Quality, safety, and transparency in every shipment
Sermorelin Inj.
Sermorelin NasalTesamorelin Inj.We work only with accredited, FDA-registered 503A pharmacies (state-licensed compounding pharmacies). Every batch is tested before shipment. Our partners exceed required standards.
Tested multiple times per week.
- Required by law: within ±10% of the correct strength
- Our results: typically within ±2%
Confirms medication is free from bacteria and other germs. Every batch tested to USP 797.1 standards (the official pharmacy sterility standard).
Assesses the acid/base balance to ensure minimal irritation upon injection.
Every batch tested for bacterial toxins (the harmful substances bacteria leave behind). Limits set by USP 85, the official pharmacy purity standard.
Start growth hormone peptide therapy with Craft Peptides.
Get StartedGrowth Hormone Peptide Therapy
Three Ways to Begin
| Sermorelin Inj. | Sermorelin Nasal | Tesamorelin Inj. | |
|---|---|---|---|
| Peptide | Sermorelin | Sermorelin | Tesamorelin |
| Strength | Standard | Standard | Strongest |
| Route | Subcutaneous | Intranasal | Subcutaneous |
| Half-life | Short | Short | Long |
| Price | $180 | $180 | $299 |
Prices are for one month supply. All ship cold-chain. After your first order, your portal unlocks 3-month bundles (10% off) and 6-month bundles (15% off). Most patients start with Sermorelin and graduate to Tesamorelin under provider guidance.
Frequently Asked Questions
HGH replaces growth hormone from outside your body. Over time, that can shut down your own production.
GHRH peptides (Sermorelin and Tesamorelin) ask your brain to release the GH it already makes, in its natural pulsing rhythm.
When you stop, your body returns to baseline. Your own production stays intact.
Both prompt your brain to release your own growth hormone. The difference is strength and duration:
- Sermorelin: gentler, shorter-acting. The classic starting point.
- Tesamorelin: stronger, longer-acting. The most potent GHRH analog, with established results on visceral fat.
Start with Sermorelin if you're new to peptides. Choose Tesamorelin if you want a stronger response or are targeting visceral fat specifically.
- Injection: highest absorption, strongest response. Best for serious recovery, body composition, and longevity goals.
- Nasal spray: needle-free, travel-friendly. Lower absorption, so your clinician calibrates the dose. Same pathway, same result type.
Many patients use both: injection at home, nasal for travel.
- Weeks 2–4: deeper sleep, better recovery
- Weeks 8–12: body composition shifts (leaner, less visceral fat)
- Months 3+: continued improvement
Tesamorelin tends to act faster. Sermorelin is a smoother, more gradual arc.
Individual response varies with age, sex, body composition, training, and nutrition.
No. This is the key advantage over HGH.
Sermorelin and Tesamorelin signal your brain to release the GH it's already making. Your natural feedback loop stays intact.
Stop the peptide, and your body returns to its prior baseline. Nothing is shut down, nothing atrophies.
- Choose your plan and complete checkout.
- Fill out the Health History form. Sent immediately after.
- Get approved. Typically within 24 hours.
Your payment is authorized but not charged unless you're approved.
No hidden fees, ever. Your price includes:
- Pre-mixed medication
- Personalized dosing
- Cold-chain shipping and supplies
- Clinician support
Yes. Bundle savings unlock in your patient portal after your first order:
- 3-month bundle: 10% off
- 6-month bundle: 15% off
We start every patient with a single first month so you can experience the protocol before committing. No obligation to bundle, many patients reorder month to month.
Within 2–6 business days of approval.
All formats require refrigeration and ship cold-chain in insulated containers with ice packs.
Yes. Sermorelin and Tesamorelin are prescription-only.
Our licensed physicians review your Health History form before any prescription is issued.
Yes. Two ways:
- Message your clinician anytime in your portal. Response within 24 hours.
- Schedule a check-in call. Unlimited, included.
Currently shipping to TX, CA, FL, NY.
Additional states added regularly.
Safety Information
Generally well-tolerated. Because these signal your brain rather than overriding it, side effects are typically mild, and tied to dose level.
Most resolve within hours, and improve further as your body adjusts.
Most side effects, if present, subside within hours. If side effects are uncomfortable, lower your dose under provider guidance.
Possible side effects of growth hormone peptide therapy include:
Possible side effects of growth hormone peptide therapy include:
- Injection site redness, warmth, or mild irritation (with injection)
- Nasal irritation, sneezing, or post-nasal drip (with nasal spray)
- Flushing
- Headache (typically transient, dose-dependent)
- Joint or muscle aching (more common with Tesamorelin, particularly at higher doses; usually resolves with dose adjustment)
- Mild fluid retention or puffiness
- Tingling or numbness in the hands (rare, dose-dependent)
- Vivid dreams (often a sign the peptide is working - reflects deeper sleep)
- Transient blood glucose elevation (your provider may monitor this with periodic labs)
Growth hormone and IGF-1 are growth signals. Specialist clearance is required before starting if you have:
- Active cancer
- Recent cancer history
- Active diabetic eye disease (retinopathy)
Our physicians will not approve therapy without specialist sign-off in these cases.
Do not use Sermorelin or Tesamorelin if you:
Cautions - speak with your provider before starting:
Medications and supplements to be aware of:
- Are pregnant, planning to become pregnant, or breastfeeding
- Have an active malignancy or a cancer history within the last 5 years (without specialist clearance)
- Have active diabetic retinopathy
- Have a known hypersensitivity to GHRH analogs or any excipient in the formulation
- Are under 18 years of age
Cautions - speak with your provider before starting:
- Diabetes or insulin resistance: GH can transiently raise blood glucose. Your provider may monitor with periodic labs.
- Hypothyroidism: Treatment should be optimized before peptide therapy.
- Carpal tunnel syndrome: Higher GH levels can occasionally exacerbate symptoms.
- Active major surgery or critical illness recovery: Postpone therapy until cleared.
Medications and supplements to be aware of:
- Glucocorticoids (prednisone, etc.) can blunt GH response - your provider will coordinate.
- Other peptide therapies are generally compatible - your provider will coordinate any combination protocol.
- Insulin and oral diabetes medications: dose adjustments may be required.
Tesamorelin (brand name Egrifta) is FDA-approved for one specific use: reducing belly fat in HIV-related fat redistribution. Using it within broader growth hormone protocols is off-label (allowed, but outside the FDA-approved use).
Sermorelin (formerly Geref) was FDA-approved for pediatric growth hormone deficiency. It was pulled from the market in 2008 for commercial reasons, not safety. Still available through compounding pharmacies (state-licensed pharmacies that mix custom medications).
Both are made by state-licensed 503A pharmacies that follow FDA guidelines. We work only with accredited 503A pharmacies that test every batch for purity, sterility, and strength.
- Veldhuis JD, Iranmanesh A, Weltman A. Elements in the pathophysiology of diminished growth hormone (GH) secretion in aging humans. Endocrine. 1997;7(1):41-48. PMID: 9449031.
- Iranmanesh A, Lizarralde G, Veldhuis JD. Age and relative adiposity are specific negative determinants of the frequency and amplitude of growth hormone (GH) secretory bursts and the half-life of endogenous GH in healthy men. JCEM. 1991;73(5):1081-1088. PMID: 1939523.
- Falutz J, et al. Effects of tesamorelin (TH9507), a growth hormone-releasing factor analog, in human immunodeficiency virus-infected patients with excess abdominal fat. NEJM. 2007;357(23):2359-2370. PMID: 18057338.
- Stanley TL, et al. Effects of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trial. JAMA. 2014;312(4):380-389. PMID: 25038357.
- Walker RF. Sermorelin: a better approach to management of adult-onset growth hormone insufficiency? Clinical Interventions in Aging. 2006;1(4):307-308. PMID: 18046908; PMCID: PMC2699646.
- Sigalos JT, Pastuszak AW. The Safety and Efficacy of Growth Hormone Secretagogues. Sexual Medicine Reviews. 2018;6(1):45-53. PMID: 28526632.
Pairs well with
Build Your Stack.
Sermorelin and Tesamorelin work along the same recovery pathway as several adjacent therapies. Stacking them amplifies what each one does on its own, and at lower doses than either would require alone.
Stack & Save. 10% off the item of least value when you stack.
Stack & SaveNAD+ Injection
Cellular energy and recovery.
Supports the same mitochondrial repair systems your brain signal activates. Patients often pair NAD+ with GHRH peptides for compounded recovery and a stronger sense of vitality.
$225
10% off the item of least value when you stack
Stack & SaveMicrodose Tirzepatide
Lose more fat, while keeping muscle.
Microdose tirzepatide reduces appetite and helps mobilize fat. Stacked with Sermorelin or Tesamorelin, the lean-mass loss problem of full-dose GLP-1 protocols largely goes away.
$140
10% off the item of least value when you stack
Stack & SaveGlutathione
The body's master antioxidant.
Supports liver detoxification and skin clarity. Many patients add glutathione during the first months of GHRH therapy to support the cellular turnover that comes with deeper recovery.
$149
10% off the item of least value when you stack
Why these stack so well with GHRH peptides.
Sermorelin and Tesamorelin work upstream, signaling your brain to release growth hormone in its natural rhythm. NAD+ works inside the cell, supporting the energy systems that GH-driven repair depends on. Microdose tirzepatide handles the appetite and fat-mobilization side that GHRH peptides don't directly address. Glutathione supports the detoxification load that increases when cellular turnover increases. Together they cover four mechanisms with one daily protocol.
Interested in growth hormone peptides?
Speak with a licensed clinician to find out whether Sermorelin or Tesamorelin is the right protocol for you.
Important
Sermorelin and Tesamorelin are compounded medications dispensed by licensed 503A pharmacies under a valid prescription. They are not FDA-approved for the uses described on this page, and are not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. Information on this page is for general education and does not replace clinical advice from your prescribing provider.